Conjugated Linoleic Acid, or CLA, is a term used to refer to a mixture of fatty acids that have the general structure of linoleic acid (18 carbons in length, 2 double bonds) where the double bonds exist two carbons away from each other; they are all polyunsaturated fatty acids, and some may be trans fatty acids.
CLA has been investigated to be a fat burner and health promoting agent due to its effect on a molecular signalling receptor family named PPAR which is related to fat burning, steroid signalling, inflammation, and glucose/lipid metabolism.
The omega-3 fatty acids you’ll get from fish oil -- eicosapentaenoic acid, or EPA, and docosahexaenoic acid, or DHA -- are healthy polyunsaturated fats. In addition to their role in the structure and function of cells throughout your body, the omega-3s reduce your risk of cardiovascular disease through multiple actions. They fight inflammation, lower blood pressure, keep blood vessels healthy, and reduce levels of cholesterol and triglycerides. They may also help prevent rheumatoid arthritis and cancer, according to the Harvard School of Public Health.
Omega-6sLike omega-3s, omega-6 fatty acids are polyunsaturated fats that reduce your levels of cholesterol. The omega-6 -- linoleic acid -- may also lower your risk for developing type 2 diabetes, according to research cited in the "Journal of the Academy of Nutrition and Dietetics" in January 2014. Vegetable oils, seeds and nuts are much better sources of the omega-6s, but they’re also found in fish oil. For example, 1 tablespoon of corn oil has 7 grams of omega-6, while wild salmon has only 0.4 grams.
Omega-9, or oleic acid, is better known as the primary fatty acid in olive oil, but you’ll also get it from the oils in fish. Salmon and trout have roughly the same amount of omega-9 as omega-3, according to Purdue University. Omega-9 is a monounsaturated fat that reduces your bad cholesterol while increasing the amount of good cholesterol in your bloodstream. Oleic acid is also an essential component of the protective covering on nerves called the myelin sheath.